All material on this website is protected by copyright, Copyright 1994-2023 by WebMD LLC. iron sucrose decreases levels of tetracycline by inhibition of GI absorption. Separate by 2 hr. The dosing for iron replacement treatment in pediatric patients with NDD-CKD or PDD-CKD has not been established. Parenteral iron supplementation. Use Caution/Monitor. Monitor Closely (1)esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Individual doses of 2 mL or less may be given on a daily basis until the calculated total amount required has been reached. Aranesp (darbepoetin alfa) | Dosing Considerations It can be expressed in mg per ml. Applies only to oral form of both agents. Minor/Significance Unknown. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. UpToDate. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Applies only to oral form of both agents. Divide the calculated dose by the patient's weight (IBW if BMI >30, or actual body weight (ABW) if BMI30) to ensure it does NOT exceed 20mg/kg. Use Caution/Monitor. Avoid or Use Alternate Drug. Monitor Closely (1)iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. Applies only to oral form of both agents. VenAccess is a trademark of Vifor (International) Inc. Switzerland. Ganzoni Equation for Iron Deficiency Anemia - MDCalc Intravenous iron sucrose: establishing a safe dose. Applies only to oral form of both agents. FERAHEME met the predefined criteria for non-inferiority to Venofer . Applies only to oral form of both agents. Parenteral Iron Replacement For Iron Deficiency Anemia Calculator Prescribing and dispensing information For iron sucrose A complex of ferric hydroxide with sucrose containing 2% (20 mg/mL) of iron. 1 Dosing for patients who weigh less than 50 kg FOR PATIENTS WEIGHING LESS THAN 50 kg: Administer Monoferric as 20 mg/kg actual body weight by intravenous infusion 20 minutes . Minor/Significance Unknown. Serious - Use Alternative (1)iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. Use Caution/Monitor. The cost of Venofer is $145 for a dose of 300 mg and Monoferric is $274 for a dose of 500mg. Serious - Use Alternative (1)iron sucrose decreases levels of doxycycline by inhibition of GI absorption. PDF Injectafer (ferric carboxymaltose injection) - Food and Drug Administration Below the form there are further instructions on how to use the calculator. IDA symptoms are often nonspecific and include tiredness, weakness, shortness of breath. Max Dose. Most Philadelphia, PA: Lippincott Williams & Wilkins;2013;303-307. Dosage Calculator Use Caution/Monitor. Minor (2)calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. Hemoglobin can be input in g/dL, g/L or mmol/L and refers to the amount of hemoglobin in the red blood cells. Fatal reactions have followed the test dose of iron dextran injection. DICP. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. 2.1 Dosage - Total dose infusion The dose calculation for CosmoFer is based on patients body weight according to the table below and is diluted in 500mLs of normal saline. Anemia; 2015: 763576. Our dosage calculator can help you with this as well. Venofer (iron sucrose) dose calculator | Calculosaurus.com Administer Venofer early during the dialysis session (generally within the first hour). Elemental iron product this is a choice between three iron supplement products: Iron dextran 50 mg/mL, Iron sucrose 20 mg/mL and Ferric gluconate 12.5 mg/mL. Use Caution/Monitor. Ferrlecit has been administered at sequential dialysis sessions by infusion or by slow intravenous injection during the dialysis session itself. Calculosaurus | Medical calculators for obstetrics and gynaecology Use the menu to browse through our clinical calculators. Minor/Significance Unknown. iron sucrose decreases levels of deferiprone by enhancing GI absorption. All Rights Reserved. Intravenous iron replacement can take place as total dose (as in the case of iron-dextran or iron carboxymaltose) or as split dose (in the case of iron sucrose). Applies only to oral form of both agents. The dosage of Venofer is expressed in mg of elemental iron. Each mL contains 20 mg of elemental iron. Minor (1)iron sucrose decreases levels of manganese by inhibition of GI absorption. Minor/Significance Unknown. The recommendation is that most adults need a cumulative dose of elemental iron of at least 1 g. Iron replenishment can be done intravenously, either as total dose (example: iron-dextran or iron carboxymaltose) or as split dose (example: iron sucrose). Minor/Significance Unknown. Applies only to oral form of both agents. Crown Rump Length and Nuchal Translucency. J Lab Clin Med. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Iron Deficiency Calculator Venofer (Iron Sucrose Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. DailyMed - VENOFER- iron sucrose injection, solution Administer while the patient is in a reclined or semi-reclined position. Manage and view all your plans together even plans in different states. Inspect parenteral drug products visually for the absence of particulate matter and discoloration prior to administration. Use Caution/Monitor. Applies only to oral form of both agents. IV iron sucrose (Venofer) given as divided dosages, and low molecular weight iron dextran (CosmoFer) this can be given as divided dose or as a total dose infusion . Do Not Copy, Distribute or otherwise Disseminate without express permission. Give each dose as 750 mg for a total cumulative dose of 1500 mg of iron per course. (1970) Intravenous iron-dextran: therapeutic and experimental possibilities. Contraindicated. Venofer treatment may be repeated if iron deficiency reoccurs. Minor (1)gymnema decreases levels of iron sucrose by inhibition of GI absorption. Minor/Significance Unknown.iron sucrose increases levels of calcium citrate by enhancing GI absorption. Venofer treatment may be repeated if necessary. rabeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Serious - Use Alternative (1)iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. The dose of Ferinject is based on calculation of ideal body weight and calculation of iron deficit using the Ganzoni formula. Applies only to oral form of both agents. Most studies have used IV iron sucrose (maximum dose of 200 mg per setting) or ferric carboxymaltose (maximum dose of 1000 mg per week). The dosing for iron replacement treatment in pediatric patients with NDD-CKD or PDDCKD has not - been established. For males: LBW = 50 kg + 2.3 kg for each inch of patients height over 5 feet For females: LBW = 45.5 kg + 2.3 kg for each inch of patients height over 5 feet. In the text below the tool there is more information on how the iron deficit is calculated. Use alternatives if available. VENOFER at IV doses up to 15 mg iron/kg/dose [about 10 times the maximum recommended human dose for a 70 kg person] given three times a week was found to have no effect on fertility . Where C= concentration of 4. Safety of highdose iron sucrose infusion in hospitalized patients with chronic kidney disease. The recommended Feraheme dose may be readministered to patients with persistent or recurrent iron deficiency anemia. Use Caution/Monitor. The therapeutic management of IDA focuses on the replenishment of the iron stores through methods that have been mentioned above. By entering this website, you acknowledge that you are a licensed healthcare professional practicing in the United States. . Modify Therapy/Monitor Closely. Hemoglobin iron deficit = 60 x (14 - 8) x (2.145) = 772 mg iron. Calculation of Iron Deficit - Perinatology.com It is usually given slowly over 2 to 5 minutes or as directed by your doctor. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. Applies only to oral form of both agents. in the colostrum of 10 iron deficient breastfeeding women who were 2 to 3 days postpartum and received a single dose of 100 mg of intravenous iron . Monitor Closely (1)aluminum hydroxide will decrease the level or effect of iron sucrose by increasing gastric pH. Ferric gluconate: 12.5 mg/mL Schrier SL, Mentzer WC, Landaw SA. Anemias. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. For iron maintenance treatment, administer Venofer, (2 years of age or older) with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment. 1996 Aug;11(4):139-46. Monitor Closely (1)vitamin E decreases levels of iron sucrose by increasing hepatic clearance. Applies only to oral form of both agents. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every two weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron carboxymaltose); Iron deficiency is common during childhood growth, prolonged periods of sickness, in convalescence or during pregnancy. Administer Venofer 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session [see How Supplied/Storage and Handling (16.2).] The iron deficit calculator is useful as one of the determinations performed before iron replenishment therapy is initiated. Do not administer Venofer to patients with evidence of iron overload. Total dose iron infusion: safety and efficacy in predialysis patients. 1) Ganzoni AM. Monitor Closely (1)deferasirox decreases levels of iron sucrose by inhibition of GI absorption. Schweiz Med Wochenschr. Deferiprone may bind polyvalent cations (eg, iron, aluminum, and zinc), separate administration by at least 4 hr between deferiprone and other medications (eg, antacids), or supplements containing these polyvalent cations. Use Caution/Monitor. Where: Medicine concentration Amount of active substance per a given volume of your drug. Administer a test INFeD dose prior to the first therapeutic dose. Applies only to oral form of both agents. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Dr. Ganzonis primary research is focused on iron deficiency and plasma iron transport. Formula for calculating the required dose of iron sucrose 1. Minor/Significance Unknown. Anemia. Applies only to oral form of both agents. The dosing for iron replacement treatment in pediatric patients with HDD-CKD has not been established. Use Caution/Monitor. This topic . Mode of Administration: Administer Venofer only intravenously by slow injection or by infusion. INFED- iron dextran injection [Package insert], Hemoglobin iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) Note: Hbg (current hemoglobin level) units: (g/dL) Alternatively: Volume of product required (mL) = [weight (kg) x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. For liquid medications, also enter the value of the Medicine Concentration and choose . Each mL contains 20 mg of elemental iron. Minor/Significance Unknown. Human studies not conducted. By taking into account the case of a patient weighing 78 kg (172 lbs) and having a hemoglobin level of 11 g/dL (110 g/L or 6.83 mmol/L). Recommended starting dose 1 Aranesp is dosed at 2.25 mcg/kg SC QW or 500 SC Q3W 1 (SC = subcutaneous) Before initiating 1: Evaluate iron status; administer supplemental iron therapy as needed Correct or eliminate other causes of anemia Initiate 1: Only when Hb < 10 g/dL
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